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Anotace knihy

This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF- from the basic principles to the practical applications. Chapters provide basic introduction of TGF- signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF- signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.§§Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field.§

Parametry knihy

Zařazení knihy Knihy v angličtině Mathematics & science Biology, life sciences Cellular biology (cytology)

• Plný název: TGF- Signaling
• Podnázev: Methods and Protocols
• Autor: Xin-Hua Feng, Pinglong Xu, Xiy Lin
• Jazyk: Angličtina
• Vazba: Pevná
• Počet stran: 394
• EAN: 9781493929658
• ISBN: 1493929658
• ID: 09300983
• Nakladatelství: Humana Press Inc.
• Hmotnost: 9992 g
• Rozměry: 254 × 178 × 20 mm
• Datum vydání: 05. November 2015

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