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Více informací o knize Role of Inteleuchin-6 in breast cancer stem-like cells

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Anotace knihy

Inflammation triggers pathological warnings in the human body including infection, autoimmune disease, metabolic syndrome and cancer. In this book the authors determine the molecular effect of the pro-inflammatory cytokine IL-6 in breast cancer. The authors describe several mechanisms by which IL-6 exposure can foster tumor progression via the expansion of a specific population of cancer cells, called cancer stem cells (CSCs). These cells represent a small fraction of each tumor and dictate tumor progression toward a pro-metastatic phenotype. The authors unravel a unique mechanism by means IL-6 mediated the conversion of non-stem cells into CSCs capable of surviving in tumor-stoma niches and hypoxic niches. Inflammation, hypoxia, CSCs and breast cancer share the up-regulation of IL-6 as a common mediator of malignancy.

Parametry knihy

• Plný název: Role of Inteleuchin-6 in breast cancer stem-like cells
• Autor: Pasquale Sansone, Massimiliano Bonafe, Gianluca Storci
• Jazyk: Angličtina
• Vazba: Brožovaná
• Počet stran: 112
• EAN: 9783330651500
• ISBN: 3330651504
• ID: 16549481
• Nakladatelství: SPS
• Hmotnost: 183 g
• Rozměry: 220 × 150 × 7 mm
• Datum vydání: 22. June 2017

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